Download Artificial Cells, Cell Engineering and Therapy by S Prakash PDF

By S Prakash

This authoritative reference offers an in depth examine of the main updated advancements in man made cells, cellphone engineering, and mobilephone remedy. damaged down into 4 sections, the booklet covers the layout, engineering, and makes use of of synthetic cells and assesses the medical relevance of synthetic cells and phone engineering. Highlights contain liposomes, nanocapsules, stem telephone engineering for treatment, phone remedy ways for spinal wire harm, remedy of melanoma, insulin supply, and pharmaceutical and to call quite a few. this can be a hugely dynamic zone with turning out to be curiosity within the use of engineered cells in managed unencumber of energetic medications and different healing brokers.

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Additional info for Artificial Cells, Cell Engineering and Therapy

Example text

3 Microcapsule design membrane materials Recognizing the complexities inherent to the process, a variety of materials has been investigated for use in microencapsulation (Fig. 3). The major polymers currently under investigation for the encapsulation of live cells include alginate, hydroxyethyl methacrylate-methyl methacrylate (HEMA-MMA) and other hydrogels, polyacrylonitrile-polyvinyl chloride (PAN-PVC), hollow fiber membranes (HFMs), siliceous encapsulates, cellulose membranes and molecular variations on each of the above.

Van Raamsdonk JM, Chang PL. Osmotic pressure test: a simple, quantitative method to assess the mechanical stability of alginate microcapsules. Journal of Biomedical Materials Research 2001; 54(2):264-271. 46. Van Raamsdonk JM, Ross CJ, Potter MA, Kurachi S, Kurachi K, Stafford DW et al. Treatment of hemophilia B in mice with nonautologous somatic gene therapeutics. Journal of Laboratory and Clinical Medicine 2002; 139(1):35±42. 47. Cirone P, Bourgeois JM, Austin RC, Chang PL. A novel approach to tumor suppression with microencapsulated recombinant cells.

Making microencapsulation work: conformal coating, immobilization gels and in vivo performance. Journal of Controlled Release 2000; 65(1±2):173±186. 4. Chang PL. Encapsulation for somatic gene therapy. Annals of the NY Academy of Science 1999; 875:146±158. Introduction to artificial cells 31 5. Lim F, Sun AM. Microencapsulated islets as bioartificial endocrine pancreas. Science 1980; 210(4472):908±910. 6. Chang TMS. Hemoglobin Corpuscles. Report of a research project for Honours Physiology. 1957.

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